Ensuring Sample Integrity: Ultra-Low Temperature Monitoring with STN’s MiraThermo Thermometer

Introduction

Ultra-low temperature freezers (-80 °C) are critical assets in pharmaceutical research, biobanking, and vaccine storage. These environments preserve biological samples, reagents, and active pharmaceutical ingredients that are highly sensitive to temperature fluctuations. Even minor deviations can result in irreversible degradation, data loss, and financial consequences.

To meet these stringent demands, STN Instruments developed the MiraThermo Thermometer, a high-accuracy, laboratory-grade temperature measurement solution designed for precise, stable, and traceable monitoring under extreme cold conditions with 24 hours, 7 days and 30 days Max/Min recording and data logging to record all data for reporting. 


Precision for Critical Cold Storage

The MiraThermo series thermometers provide exceptional measurement accuracy, reaching ±0.1 °C (high accuracy) or ±0.2°C (Accurate) when paired with a calibrated platinum resistance thermometer (PRT). Its wide measurement ranges from -200°C to +200°C (-90°C to 50°C, -90°C to 200°C, -200°C to 0°C optional) ensure reliable performance across liquid nitrogen, ultra-low freezers, low temperature freezers, refrigerated chambers, and ambient laboratory environments alike.

By employing low-drift sensing technology and a high-resolution analog-to-digital converter, the MiraThermo series thermometers maintain stability over long-term operation, an essential attribute when monitoring freezers that operate continuously for years.


Reliable Design for Harsh Conditions

Unlike standard thermometers that lose precision in deep-cold environments, MiraThermo series thermometers’ sensor assemblies are optimized for thermal equilibrium and low self-heating effects.
When used with STN’s Stainless-Steel Thermal Capsule, the system acts as a liquid-free thermal buffer, damping transient fluctuations caused by door openings or defrost cycles. This approach reflects the true storage temperature experienced by stored materials, preventing false alarms and ensuring meaningful monitoring data.


Calibration and Traceability

All MiraThermo thermometers are calibrated conforming to ISO/IEC 17025 standards, ensuring measurement confidence for compliance with FDA, CDC, WHO, and USP temperature monitoring requirements.
For quality systems such as GMP, GLP, and ISO 9001, traceable temperature records are vital for audits and verification. MiraThermo thermometers’ calibration certificates provide the documentation needed for full traceability through the measurement chain.


Application in Vaccine and Biobank Storage

In vaccine development and research, maintaining the cold chain at -80 °C is non-negotiable. MiraThermo thermometers ensure that any deviation outside the prescribed range is detected and addressed before it impacts product integrity.
For biobank samples stored long-term, stable and accurate monitoring reduces the risk of unnoticed freezer malfunctions and preserves valuable biological materials for future use.


Future Integration and Digital Capabilities

STN Instruments is expanding the MiraThermo series thermometers line with

WI-FI connectivity, and cloud-based dashboards from Mobile App and webpage (Target completion: End of March 2026) that will allow remote access to real-time temperature records. Integration with alarm systems and AI-driven anomaly prediction will further enhance monitoring reliability and proactive maintenance.


Conclusion

The STN MiraThermo Thermometer provides laboratories and pharmaceutical facilities with the accuracy, traceability, and stability needed for reliable -80 °C freezer monitoring. Together with STN’s Thermal Capsule and data recording modules, it forms a complete, compliant solution for critical cold-chain management.

STN Instruments — Reliable Measurement for a Trusted World.
🌐 Learn more: www.stninstruments.com

 

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